Runes are dropped from (where, how, etc.?)
Runes can be melted (?) at the rune smithy (?) in Cities (image) into powerful Artifacts for weapons.
Usually distinguished as "Rune Artifacts" "Soul Artifacts" and "Relic Artifacts", these crafting ingredients are part the recipe of the most powerful weapons in Albion.
Runes can also be used for..
List of Runes
Adept's Rune Expert's Rune Master's Rune Grandmaster's Rune Elder's Rune